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Role of Paralogue of XRCC4 and XLF in DNA Damage Repair and Cancer Development

Non-homologous end joining (cNHEJ) is a major pathway to repair double-strand breaks (DSBs) in DNA. Several core cNHEJ are involved in the progress of the repair such as KU70 and 80, DNA-dependent protein kinase catalytic subunit (DNA-PKcs), Artemis, X-ray repair cross-complementing protein 4 (XRCC4...

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Detalles Bibliográficos
Autores principales: Tang, Jialin, Li, Zhongxia, Wu, Qiong, Irfan, Muhammad, Li, Weili, Liu, Xiangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926060/
https://www.ncbi.nlm.nih.gov/pubmed/35309348
http://dx.doi.org/10.3389/fimmu.2022.852453