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Circulating Cell-Free DNA Captures the Intratumor Heterogeneity in Multinodular Hepatocellular Carcinoma

Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, with more than 40% of patients initially diagnosed with multinodular HCCs. Although circulating cell-free DNA (cfDNA) has been shown to effectively detect somatic mutations, little is known about its utility to capture intratumor hete...

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Detalles Bibliográficos
Autores principales: Coto-Llerena, Mairene, Benjak, Andrej, Gallon, John, Meier, Marie-Anne, Boldanova, Tuyana, Terracciano, Luigi M., Ng, Charlotte K.Y., Piscuoglio, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926063/
https://www.ncbi.nlm.nih.gov/pubmed/35263170
http://dx.doi.org/10.1200/PO.21.00335