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Circulating Cell-Free DNA Captures the Intratumor Heterogeneity in Multinodular Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is a highly heterogeneous disease, with more than 40% of patients initially diagnosed with multinodular HCCs. Although circulating cell-free DNA (cfDNA) has been shown to effectively detect somatic mutations, little is known about its utility to capture intratumor hete...
Autores principales: | Coto-Llerena, Mairene, Benjak, Andrej, Gallon, John, Meier, Marie-Anne, Boldanova, Tuyana, Terracciano, Luigi M., Ng, Charlotte K.Y., Piscuoglio, Salvatore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926063/ https://www.ncbi.nlm.nih.gov/pubmed/35263170 http://dx.doi.org/10.1200/PO.21.00335 |
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