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Periductal bile acid exposure causes cholangiocyte injury and fibrosis

INTRODUCTION: Bile duct integrity is essential for the maintenance of the structure and function of the biliary tree. We previously showed that cholangiocyte injury in a toxic model of biliary atresia leads to increased monolayer permeability. Increased epithelial permeability was also shown in othe...

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Detalles Bibliográficos
Autores principales: Dotan, Miri, Fried, Sophia, Har-Zahav, Adi, Shamir, Raanan, Wells, Rebecca G., Waisbourd-Zinman, Orith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926245/
https://www.ncbi.nlm.nih.gov/pubmed/35294492
http://dx.doi.org/10.1371/journal.pone.0265418