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Methylation pattern of polymorphically imprinted nc886 is not conserved across mammalia

BACKGROUND: In humans, the nc886 locus is a polymorphically imprinted metastable epiallele. Periconceptional conditions have an effect on the methylation status of nc886, and further, this methylation status is associated with health outcomes in later life, in line with the Developmental Origins of...

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Detalles Bibliográficos
Autores principales: Kostiniuk, Daria, Tamminen, Hely, Mishra, Pashupati P., Marttila, Saara, Raitoharju, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926257/
https://www.ncbi.nlm.nih.gov/pubmed/35294436
http://dx.doi.org/10.1371/journal.pone.0261481