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The metalloprotease ADM-4/ADAM17 promotes axonal repair

Axonal fusion is an efficient means of repair following axonal transection, whereby the regenerating axon fuses with its own separated axonal fragment to restore neuronal function. Despite being described over 50 years ago, its molecular mechanisms remain poorly understood. Here, we demonstrate that...

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Detalles Bibliográficos
Autores principales: Ho, Xue Yan, Coakley, Sean, Amor, Rumelo, Anggono, Victor, Hilliard, Massimo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926332/
https://www.ncbi.nlm.nih.gov/pubmed/35294233
http://dx.doi.org/10.1126/sciadv.abm2882