Assembly mechanism of early Hsp90-Cdc37-kinase complexes

Molecular chaperones have an essential role for the maintenance of a balanced protein homeostasis. Here, we investigate how protein kinases are recruited and loaded to the Hsp90-Cdc37 complex, the first step during Hsp90-mediated chaperoning that leads to enhanced client kinase stability and activat...

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Detalles Bibliográficos
Autores principales: Keramisanou, Dimitra, Vasantha Kumar, M.V., Boose, Nicole, Abzalimov, Rinat R., Gelis, Ioannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926337/
https://www.ncbi.nlm.nih.gov/pubmed/35294247
http://dx.doi.org/10.1126/sciadv.abm9294

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926337/
https://www.ncbi.nlm.nih.gov/pubmed/35294247
http://dx.doi.org/10.1126/sciadv.abm9294

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