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Membrane repair triggered by cholesterol-dependent cytolysins is activated by mixed lineage kinases and MEK

Repair of plasma membranes damaged by bacterial pore-forming toxins, such as streptolysin O or perfringolysin O, during septic cardiomyopathy or necrotizing soft tissue infections is mediated by several protein families. However, the activation of these proteins downstream of ion influx is poorly un...

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Detalles Bibliográficos
Autores principales: Ray, Sucharit, Roth, Robyn, Keyel, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926344/
https://www.ncbi.nlm.nih.gov/pubmed/35294243
http://dx.doi.org/10.1126/sciadv.abl6367