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In Vitro and In Vivo Evaluations of Berberine-Loaded Microparticles Filled In-House 3D Printed Hollow Capsular Device for Improved Oral Bioavailability

The low oral bioavailability, short biological half-life, high dose, and frequent dosing of berberine (BBR) contribute to its restricted clinical use despite its extensive pharmacological activity. Thus, the objective of this study was to formulate sustained-release microparticles (MPs) using a pH-i...

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Detalles Bibliográficos
Autores principales: Choudhury, Dinesh, Jala, Aishwarya, Murty, Upadhyayula Suryanarayana, Borkar, Roshan M., Banerjee, Subham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926385/
https://www.ncbi.nlm.nih.gov/pubmed/35296955
http://dx.doi.org/10.1208/s12249-022-02241-9