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Tom70-based transcriptional regulation of mitochondrial biogenesis and aging

Mitochondrial biogenesis has two major steps: the transcriptional activation of nuclear genome-encoded mitochondrial proteins and the import of nascent mitochondrial proteins that are synthesized in the cytosol. These nascent mitochondrial proteins are aggregation-prone and can cause cytosolic prote...

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Detalles Bibliográficos
Autores principales: Liu, Qingqing, Chang, Catherine E, Wooldredge, Alexandra C, Fong, Benjamin, Kennedy, Brian K, Zhou, Chuankai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926401/
https://www.ncbi.nlm.nih.gov/pubmed/35234609
http://dx.doi.org/10.7554/eLife.75658