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Equine immunoglobulin fragment F(ab’)(2) displays high neutralizing capability against multiple SARS-CoV-2 variants

Neutralizing antibody-based passive immunotherapy could be an important therapeutic option against COVID-19. Herein, we demonstrate that equines hyper-immunized with chemically inactivated SARS-CoV-2 elicited high antibody titers with a strong virus-neutralizing potential, and F(ab’)(2) fragments pu...

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Detalles Bibliográficos
Autores principales: Gupta, Divya, Ahmed, Farhan, Tandel, Dixit, Parthasarathy, Haripriya, Vedagiri, Dhiviya, Sah, Vishal, Krishna Mohan, B., Khan, Rafiq Ahmad, Kondiparthi, Chiranjeevi, Savari, Prabhudas, Jain, Sandesh, Reddy, Shashikala, Kumar, Jerald Mahesh, Khan, Nooruddin, Harshan, Krishnan Harinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926440/
https://www.ncbi.nlm.nih.gov/pubmed/35306171
http://dx.doi.org/10.1016/j.clim.2022.108981