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Validated HPLC-UV Method for Simultaneous Estimation of Paclitaxel and Doxorubicin Employing Ion Pair Chromatography: Application in Formulation Development and Pharmacokinetic Studies

Though paclitaxel (PTX) and doxorubicin (DOX) are amongst the most widely used and investigated drug pair for combination chemotherapy but surprisingly, not a single validated HPLC-UV method is available to analyze PTX and DOX simultaneously. So, herein a HPLC-UV method is developed and validated fo...

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Detalles Bibliográficos
Autores principales: Saklani, Ravi, Tiwari, Amrendra K., Yadav, Pavan K., Yadav, Pooja, Chourasia, Manish K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8926476/
https://www.ncbi.nlm.nih.gov/pubmed/35309174
http://dx.doi.org/10.1155/2022/7708235