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Predictive Simulations in Preclinical Oncology to Guide the Translation of Biologics
Preclinical in vivo studies form the cornerstone of drug development and translation, bridging in vitro experiments with first-in-human trials. However, despite the utility of animal models, translation from the bench to bedside remains difficult, particularly for biologics and agents with unique me...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927291/ https://www.ncbi.nlm.nih.gov/pubmed/35308243 http://dx.doi.org/10.3389/fphar.2022.836925 |