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Development of an Adeno-Associated Virus-Vectored SARS-CoV-2 Vaccine and Its Immunogenicity in Mice

Owing to the outbreak of the novel coronavirus (SARS-CoV-2) worldwide at the end of 2019, the development of a SARS-CoV-2 vaccine became an urgent need. In this study, we developed a type 9 adeno-associated virus vectored vaccine candidate expressing a dimeric receptor binding domain (RBD) of the SA...

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Detalles Bibliográficos
Autores principales: Qin, Xi, Li, Shanhu, Li, Xiang, Pei, Dening, Liu, Yu, Ding, Youxue, Liu, Lan, Bi, Hua, Shi, Xinchang, Guo, Ying, Fang, Enyue, Huang, Fang, Yu, Lei, Zhu, Liuqiang, An, Yifang, Valencia, C. Alexander, Li, Yuhua, Dong, Biao, Zhou, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927296/
https://www.ncbi.nlm.nih.gov/pubmed/35310850
http://dx.doi.org/10.3389/fcimb.2022.802147