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Corticosterone induces discrete epigenetic signatures in the dorsal and ventral hippocampus that depend upon sex and genotype: focus on methylated Nr3c1 gene

The genomic effects of circulating glucocorticoids are particularly relevant in cortico-limbic structures, which express a high concentration of steroid hormone receptors. To date, no studies have investigated genomic differences in hippocampal subregions, namely the dorsal (dHPC) and ventral (vHPC)...

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Detalles Bibliográficos
Autores principales: Caradonna, Salvatore G., Einhorn, Nathan R., Saudagar, Vikram, Khalil, Huzefa, Petty, Gordon H., Lihagen, Axel, LeFloch, Claire, Lee, Francis S., Akil, Huda, Guidotti, Alessandro, McEwen, Bruce S., Gatta, Eleonora, Marrocco, Jordan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927334/
https://www.ncbi.nlm.nih.gov/pubmed/35296634
http://dx.doi.org/10.1038/s41398-022-01864-7