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Corticosterone induces discrete epigenetic signatures in the dorsal and ventral hippocampus that depend upon sex and genotype: focus on methylated Nr3c1 gene
The genomic effects of circulating glucocorticoids are particularly relevant in cortico-limbic structures, which express a high concentration of steroid hormone receptors. To date, no studies have investigated genomic differences in hippocampal subregions, namely the dorsal (dHPC) and ventral (vHPC)...
Autores principales: | Caradonna, Salvatore G., Einhorn, Nathan R., Saudagar, Vikram, Khalil, Huzefa, Petty, Gordon H., Lihagen, Axel, LeFloch, Claire, Lee, Francis S., Akil, Huda, Guidotti, Alessandro, McEwen, Bruce S., Gatta, Eleonora, Marrocco, Jordan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927334/ https://www.ncbi.nlm.nih.gov/pubmed/35296634 http://dx.doi.org/10.1038/s41398-022-01864-7 |
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