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Transcriptome analysis reveals upregulation of immune response pathways at the invasive tumour front of metastatic seminoma germ cell tumours

BACKGROUND: Testicular germ cell tumours (TGCTs) have a high metastasis rate. However, the mechanisms related to their invasion, progression and metastasis are unclear. Therefore, we investigated gene expression changes that might be linked to metastasis in seminomatous testicular germ cell tumour (...

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Detalles Bibliográficos
Autores principales: Nestler, Tim, Dalvi, Priya, Haidl, Friederike, Wittersheim, Maike, von Brandenstein, Melanie, Paffenholz, Pia, Wagener-Ryczek, Svenja, Pfister, David, Koitzsch, Ulrike, Hellmich, Martin, Buettner, Reinhard, Odenthal, Margarete, Heidenreich, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927344/
https://www.ncbi.nlm.nih.gov/pubmed/35022523
http://dx.doi.org/10.1038/s41416-021-01621-5