Machine learning discovery of missing links that mediate alternative branches to plant alkaloids

Engineering the microbial production of secondary metabolites is limited by the known reactions of correctly annotated enzymes. Therefore, the machine learning discovery of specialized enzymes offers great potential to expand the range of biosynthesis pathways. Benzylisoquinoline alkaloid production...

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Detalles Bibliográficos
Autores principales: Vavricka, Christopher J., Takahashi, Shunsuke, Watanabe, Naoki, Takenaka, Musashi, Matsuda, Mami, Yoshida, Takanobu, Suzuki, Ryo, Kiyota, Hiromasa, Li, Jianyong, Minami, Hiromichi, Ishii, Jun, Tsuge, Kenji, Araki, Michihiro, Kondo, Akihiko, Hasunuma, Tomohisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927377/
https://www.ncbi.nlm.nih.gov/pubmed/35296652
http://dx.doi.org/10.1038/s41467-022-28883-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927377/
https://www.ncbi.nlm.nih.gov/pubmed/35296652
http://dx.doi.org/10.1038/s41467-022-28883-8

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