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Precision drugging of the MAPK pathway in head and neck cancer

The mitogen-activating protein kinase (MAPK) pathway is central for cell proliferation, differentiation, and senescence. In human, germline defects of the pathway contribute to developmental and congenital head and neck disorders. Nearly 1/5 of head and neck squamous cell carcinoma (HNSCC) harbors M...

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Detalles Bibliográficos
Autores principales: Ngan, Hoi-Lam, Law, Chun-Ho, Choi, Yannie Chung Yan, Chan, Jenny Yu-Sum, Lui, Vivian Wai Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927572/
https://www.ncbi.nlm.nih.gov/pubmed/35296678
http://dx.doi.org/10.1038/s41525-022-00293-1