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Precision drugging of the MAPK pathway in head and neck cancer
The mitogen-activating protein kinase (MAPK) pathway is central for cell proliferation, differentiation, and senescence. In human, germline defects of the pathway contribute to developmental and congenital head and neck disorders. Nearly 1/5 of head and neck squamous cell carcinoma (HNSCC) harbors M...
Autores principales: | Ngan, Hoi-Lam, Law, Chun-Ho, Choi, Yannie Chung Yan, Chan, Jenny Yu-Sum, Lui, Vivian Wai Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927572/ https://www.ncbi.nlm.nih.gov/pubmed/35296678 http://dx.doi.org/10.1038/s41525-022-00293-1 |
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