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Medial prefrontal cortex and anteromedial thalamus interaction regulates goal-directed behavior and dopaminergic neuron activity

The prefrontal cortex is involved in goal-directed behavior. Here, we investigate circuits of the PFC regulating motivation, reinforcement, and its relationship to dopamine neuron activity. Stimulation of medial PFC (mPFC) neurons in mice activated many downstream regions, as shown by fMRI. Axonal t...

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Detalles Bibliográficos
Autores principales: Yang, Chen, Hu, Yuzheng, Talishinsky, Aleksandr D., Potter, Christian T., Calva, Coleman B., Ramsey, Leslie A., Kesner, Andrew J., Don, Reuben F., Junn, Sue, Tan, Aaron, Pierce, Anne F., Nicolas, Céline, Arima, Yosuke, Lee, Seung-Chan, Su, Conghui, Coudriet, Jensine M., Mejia-Aponte, Carlos A., Wang, Dong V., Lu, Hanbing, Yang, Yihong, Ikemoto, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927595/
https://www.ncbi.nlm.nih.gov/pubmed/35296648
http://dx.doi.org/10.1038/s41467-022-28892-7