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CAF-Associated Paracrine Signaling Worsens Outcome and Potentially Contributes to Chemoresistance in Epithelial Ovarian Cancer

BACKGROUND: High-grade serous ovarian cancer (HGSOC) is the predominant and deadliest form of ovarian cancer. Some of its histological subtypes can be distinguished by frequent occurrence of cancer-associated myofibroblasts (CAFs) and desmoplastic stroma reaction (DSR). In this study, we want to exp...

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Detalles Bibliográficos
Autores principales: Wessolly, Michael, Mairinger, Elena, Borchert, Sabrina, Bankfalvi, Agnes, Mach, Pawel, Schmid, Kurt Werner, Kimmig, Rainer, Buderath, Paul, Mairinger, Fabian Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927667/
https://www.ncbi.nlm.nih.gov/pubmed/35311102
http://dx.doi.org/10.3389/fonc.2022.798680