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Molecular Insights Into Binding and Activation of the Human KCNQ2 Channel by Retigabine

Voltage-gated potassium channels of the Kv7.x family are involved in a plethora of biological processes across many tissues in animals, and their misfunctioning could lead to several pathologies ranging from diseases caused by neuronal hyperexcitability, such as epilepsy, or traumatic injuries and p...

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Detalles Bibliográficos
Autores principales: Garofalo, Barbara, Bonvin, Alexandre M.J.J., Bosin, Andrea, Di Giorgio, Francesco P., Ombrato, Rosella, Vargiu, Attilio V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927717/
https://www.ncbi.nlm.nih.gov/pubmed/35309507
http://dx.doi.org/10.3389/fmolb.2022.839249