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SARS-CoV-2 spike E156G/Δ157-158 mutations contribute to increased infectivity and immune escape

Breakthrough infections by emerging SARS-CoV-2 variants raise significant concerns. Here, we sequence-characterized the spike gene from breakthrough infections that corresponded to B.1.617 sublineage. Delineating the functional impact of spike mutations revealed that N-terminal domain (NTD)-specific...

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Detalles Bibliográficos
Autores principales: Mishra, Tarun, Dalavi, Rishikesh, Joshi, Garima, Kumar, Atul, Pandey, Pankaj, Shukla, Sanjeev, Mishra, Ram K, Chande, Ajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927725/
https://www.ncbi.nlm.nih.gov/pubmed/35296517
http://dx.doi.org/10.26508/lsa.202201415