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5-HT(1F) Receptor Agonist Ameliorates Mechanical Allodynia in Neuropathic Pain via Induction of Mitochondrial Biogenesis and Suppression of Neuroinflammation

Neuropathic pain is a devastating disease that affects millions of people worldwide. Serotonin (5-hydroxytryptamine, 5-HT) is involved in pain modulation. Several lines of evidence have indicated that 5-HT(1F) receptor agonists are potent inducers of mitochondrial biogenesis. In this study, we teste...

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Detalles Bibliográficos
Autores principales: Zhang, Long-Qing, Zhou, Ya-Qun, Li, Jia-Yan, Sun, Jia, Zhang, Shuang, Wu, Jia-Yi, Gao, Shao-Jie, Tian, Xue-Bi, Mei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927783/
https://www.ncbi.nlm.nih.gov/pubmed/35308244
http://dx.doi.org/10.3389/fphar.2022.834570