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USP30: Structure, Emerging Physiological Role, and Target Inhibition

Ubiquitin-specific protease 30 (USP30) is a deubiquitinating enzyme (DUB) belonging to the USP subfamily, which was found localized in the mitochondrial outer membrane and peroxisomes owing to its unique transmembrane domain. Structural study revealed that USP30 employed a unique catalytic triad and...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Gao, Yu, Zhou, Lihui, Chen, Junhao, Xie, Zhiyan, Ye, Zifan, Wang, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927814/
https://www.ncbi.nlm.nih.gov/pubmed/35308234
http://dx.doi.org/10.3389/fphar.2022.851654