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The minor allele of the CREBRF rs373863828 p.R457Q coding variant is associated with reduced levels of myostatin in males: Implications for body composition

OBJECTIVE: The minor allele (A) of the rs373863828 variant (p.Arg457Gln) in CREBRF is restricted to indigenous peoples of the Pacific islands (including New Zealand Māori and peoples of Polynesia), with a frequency of up to 25% in these populations. This allele associates with a large increase in bo...

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Detalles Bibliográficos
Autores principales: Lee, Kate, Vakili, Sanaz, Burden, Hannah J., Adams, Shannon, Smith, Greg C., Kulatea, Braydon, Wright-McNaughton, Morag, Sword, Danielle, Watene-O’Sullivan, Conor, Atiola, Robert D., Paul, Ryan G., Plank, Lindsay D., Kallingappa, Prasanna, King, Frances, Wilcox, Phillip, Merriman, Tony R., Krebs, Jeremy D., Hall, Rosemary M., Murphy, Rinki, Merry, Troy L., Shepherd, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927835/
https://www.ncbi.nlm.nih.gov/pubmed/35218947
http://dx.doi.org/10.1016/j.molmet.2022.101464