Improving CAR-T immunotherapy: Overcoming the challenges of T cell exhaustion

Chimeric antigen receptor (CAR) T cell therapy has emerged as a cancer treatment with enormous potential, demonstrating impressive antitumor activity in the treatment of hematological malignancies. However, CAR T cell exhaustion is a major limitation to their efficacy, particularly in the applicatio...

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Detalles Bibliográficos
Autores principales: Gumber, Diana, Wang, Leo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927848/
https://www.ncbi.nlm.nih.gov/pubmed/35301179
http://dx.doi.org/10.1016/j.ebiom.2022.103941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927848/
https://www.ncbi.nlm.nih.gov/pubmed/35301179
http://dx.doi.org/10.1016/j.ebiom.2022.103941

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