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Improving CAR-T immunotherapy: Overcoming the challenges of T cell exhaustion
Chimeric antigen receptor (CAR) T cell therapy has emerged as a cancer treatment with enormous potential, demonstrating impressive antitumor activity in the treatment of hematological malignancies. However, CAR T cell exhaustion is a major limitation to their efficacy, particularly in the applicatio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927848/ https://www.ncbi.nlm.nih.gov/pubmed/35301179 http://dx.doi.org/10.1016/j.ebiom.2022.103941 |