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Enhanced production of l-sorbose by systematic engineering of dehydrogenases in Gluconobacter oxydans

l-Sorbose is an essential intermediate for the industrial production of vitamin C (l-ascorbic acid). However, the formation of fructose and some unknown by-products significantly reduces the conversion ratio of D-sorbitol to l-sorbose. This study aimed to identify the key D-sorbitol dehydrogenases i...

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Detalles Bibliográficos
Autores principales: Liu, Li, Chen, Yue, Yu, Shiqin, Chen, Jian, Zhou, Jingwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927921/
https://www.ncbi.nlm.nih.gov/pubmed/35356389
http://dx.doi.org/10.1016/j.synbio.2022.02.008