Potential enhancement of metformin hydrochloride in solidified reverse micellar solution-based PEGylated lipid nanoparticles targeting therapeutic efficacy in diabetes treatment

Metformin hydrochloride (MH) is a widely used oral biguanide antihyperglycemic (antidiabetic) drug with poor bioavailability which necessitates the development of novel drug delivery systems such as PEGylated solid lipid nanoparticles for improving its therapeutic activity. The aim of this study was...

Descripción completa

Detalles Bibliográficos
Autores principales: Kenechukwu, Franklin Chimaobi, Nnamani, Daniel Okwudili, Duhu, Judith Chekwube, Nmesirionye, Bright Ugochukwu, Momoh, Mumuni Audu, Akpa, Paul Achile, Attama, Anthony Amaechi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927942/
https://www.ncbi.nlm.nih.gov/pubmed/35309393
http://dx.doi.org/10.1016/j.heliyon.2022.e09099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927942/
https://www.ncbi.nlm.nih.gov/pubmed/35309393
http://dx.doi.org/10.1016/j.heliyon.2022.e09099

Ejemplares similares