Prion-like domains drive CIZ1 assembly formation at the inactive X chromosome

CIZ1 forms large assemblies at the inactive X chromosome (Xi) in female fibroblasts in an Xist lncRNA-dependent manner and is required for accurate maintenance of polycomb targets genome-wide. Here we address requirements for assembly formation and show that CIZ1 undergoes two direct interactions wi...

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Detalles Bibliográficos
Autores principales: Sofi, Sajad, Williamson, Louisa, Turvey, Gabrielle L., Scoynes, Charlotte, Hirst, Claire, Godwin, Jonathan, Brockdorff, Neil, Ainscough, Justin, Coverley, Dawn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927971/
https://www.ncbi.nlm.nih.gov/pubmed/35289833
http://dx.doi.org/10.1083/jcb.202103185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927971/
https://www.ncbi.nlm.nih.gov/pubmed/35289833
http://dx.doi.org/10.1083/jcb.202103185

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