Chronic exposure to ambient traffic-related air pollution (TRAP) alters gut microbial abundance and bile acid metabolism in a transgenic rat model of Alzheimer’s disease

BACKGROUND: Traffic-related air pollution (TRAP) is linked to increased risk for age-related dementia, including Alzheimer’s disease (AD). The gut microbiome is posited to influence AD risk, and an increase in microbial-derived secondary bile acids (BAs) is observed in AD patients. We recently repor...

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Detalles Bibliográficos
Autores principales: Dutta, Moumita, Weigel, Kris M., Patten, Kelley T., Valenzuela, Anthony E., Wallis, Christopher, Bein, Keith J., Wexler, Anthony S., Lein, Pamela J., Cui, Julia Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927974/
https://www.ncbi.nlm.nih.gov/pubmed/35310146
http://dx.doi.org/10.1016/j.toxrep.2022.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8927974/
https://www.ncbi.nlm.nih.gov/pubmed/35310146
http://dx.doi.org/10.1016/j.toxrep.2022.03.003

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