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β-Glucuronidase Pattern Predicted From Gut Metagenomes Indicates Potentially Diversified Pharmacomicrobiomics

β-glucuronidases (GUS) of intestinal bacteria remove glucuronic acid from glucoronides, reversing phase II metabolism of the liver and affecting the level of active deconjugated metabolites deriving from drugs or xenobiotics. Two hundred seventy-nine non-redundant GUS sequences are known in the gut...

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Detalles Bibliográficos
Autores principales: Candeliere, Francesco, Raimondi, Stefano, Ranieri, Raffaella, Musmeci, Eliana, Zambon, Alfonso, Amaretti, Alberto, Rossi, Maddalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928169/
https://www.ncbi.nlm.nih.gov/pubmed/35308380
http://dx.doi.org/10.3389/fmicb.2022.826994