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β-Glucuronidase Pattern Predicted From Gut Metagenomes Indicates Potentially Diversified Pharmacomicrobiomics
β-glucuronidases (GUS) of intestinal bacteria remove glucuronic acid from glucoronides, reversing phase II metabolism of the liver and affecting the level of active deconjugated metabolites deriving from drugs or xenobiotics. Two hundred seventy-nine non-redundant GUS sequences are known in the gut...
Autores principales: | Candeliere, Francesco, Raimondi, Stefano, Ranieri, Raffaella, Musmeci, Eliana, Zambon, Alfonso, Amaretti, Alberto, Rossi, Maddalena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928169/ https://www.ncbi.nlm.nih.gov/pubmed/35308380 http://dx.doi.org/10.3389/fmicb.2022.826994 |
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