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Biochemical Characterization of a Human Septin Octamer

Septins are part of the cytoskeleton and polymerize into non-polar filaments of heteromeric hexamers or octamers. They belong to the class of P-loop GTPases but the roles of GTP binding and hydrolysis on filament formation and dynamics are not well understood. The basic human septin building block i...

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Detalles Bibliográficos
Autores principales: Fischer, Martin, Frank, Dominik, Rösler, Reinhild, Johnsson, Nils, Gronemeyer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928218/
https://www.ncbi.nlm.nih.gov/pubmed/35309913
http://dx.doi.org/10.3389/fcell.2022.771388