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Coenzyme Q10 deficiency can be expected to compromise Sirt1 activity

For reasons that remain unclear, endogenous synthesis and tissue levels of coenzyme Q10 (CoQ10) tend to decline with increasing age in at least some tissues. When CoQ10 levels are sufficiently low, this compromises the efficiency of the mitochondrial electron transport chain, such that production of...

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Detalles Bibliográficos
Autores principales: DiNicolantonio, James J, McCarty, Mark F, O'Keefe, James H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928362/
https://www.ncbi.nlm.nih.gov/pubmed/35296520
http://dx.doi.org/10.1136/openhrt-2021-001927