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Immune system and intestinal microbiota determine efficacy of androgen deprivation therapy against prostate cancer

BACKGROUND: Prostate cancer (PC) responds to androgen deprivation therapy (ADT) usually in a transient fashion, progressing from hormone-sensitive PC (HSPC) to castration-resistant PC (CRPC). We investigated a mouse model of PC as well as specimens from PC patients to unravel an unsuspected contribu...

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Detalles Bibliográficos
Autores principales: Terrisse, Safae, Goubet, Anne-Gaelle, Ueda, Kousuke, Thomas, Andrew Maltez, Quiniou, Valentin, Thelemaque, Cassandra, Dunsmore, Garett, Clave, Emmanuel, Gamat-Huber, Melissa, Yonekura, Satoru, Ferrere, Gladys, Rauber, Conrad, Pham, Hang Phuong, Fahrner, Jean-Eudes, Pizzato, Eugenie, Ly, Pierre, Fidelle, Marine, Mazzenga, Marine, Costa Silva, Carolina Alves, Armanini, Federica, Pinto, Federica, Asnicar, Francesco, Daillère, Romain, Derosa, Lisa, Richard, Corentin, Blanchard, Pierre, Routy, Bertrand, Culine, Stéphane, Opolon, Paule, Silvin, Aymeric, Ginhoux, Florent, Toubert, Antoine, Segata, Nicola, McNeel, Douglas G, Fizazi, Karim, Kroemer, Guido, Zitvogel, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928383/
https://www.ncbi.nlm.nih.gov/pubmed/35296557
http://dx.doi.org/10.1136/jitc-2021-004191