Cancer Therapy With TCR-Engineered T Cells: Current Strategies, Challenges, and Prospects

To redirect T cells against tumor cells, T cells can be engineered ex vivo to express cancer-antigen specific T cell receptors (TCRs), generating products known as TCR-engineered T cells (TCR T). Unlike chimeric antigen receptors (CARs), TCRs recognize HLA-presented peptides derived from proteins of...

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Detalles Bibliográficos
Autores principales: Shafer, Paul, Kelly, Lauren M., Hoyos, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928448/
https://www.ncbi.nlm.nih.gov/pubmed/35309357
http://dx.doi.org/10.3389/fimmu.2022.835762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928448/
https://www.ncbi.nlm.nih.gov/pubmed/35309357
http://dx.doi.org/10.3389/fimmu.2022.835762

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