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Synthesis of Endocyclic Cycloalkyne Amino Acids

[Image: see text] “Click-ligation” is a widely adopted and valuable means to ligate biomolecules whereby two appended biologically inert moieties, such as alkynes and azides, link by cycloaddition. For terminal alkynes, Cu(+1) catalysis is required which degrades oligonucleotides by catalyzing their...

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Detalles Bibliográficos
Autor principal: Rothman, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928491/
https://www.ncbi.nlm.nih.gov/pubmed/35309419
http://dx.doi.org/10.1021/acsomega.2c00270