Access to β-Alkylated γ-Functionalized Ketones via Conjugate Additions to Arylideneisoxazol-5-ones and Mo(CO)(6)-Mediated Reductive Cascade Reactions

[Image: see text] 1,4-Conjugate addition of ((chloromethyl)sulfonyl)benzenes to arylideneisoxazol-5-ones, followed by one-pot, N-selective trapping in the presence of electrophiles, was investigated. This strategy led to the synthesis of new, stable N-protected isoxazol-5-ones in good yields and hig...

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Detalles Bibliográficos
Autores principales: Macchia, Antonio, Summa, Francesco F., Monaco, Guglielmo, Eitzinger, Andreas, Ofial, Armin R., Di Mola, Antonia, Massa, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928520/
https://www.ncbi.nlm.nih.gov/pubmed/35309475
http://dx.doi.org/10.1021/acsomega.1c07081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928520/
https://www.ncbi.nlm.nih.gov/pubmed/35309475
http://dx.doi.org/10.1021/acsomega.1c07081

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