Cargando…

Dual effect of TAT functionalized DHAH lipid nanoparticles with neurotrophic factors in human BBB and microglia cultures

BACKGROUND: Neurodegenerative diseases (NDs) are an accelerating global health problem. Nevertheless, the stronghold of the brain- the blood–brain barrier (BBB) prevents drug penetrance and dwindles effective treatments. Therefore, it is crucial to identify Trojan horse-like drug carriers that can e...

Descripción completa

Detalles Bibliográficos
Autores principales: Hernando, Sara, Nikolakopoulou, Polyxeni, Voulgaris, Dimitrios, Hernandez, Rosa Maria, Igartua, Manoli, Herland, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928663/
https://www.ncbi.nlm.nih.gov/pubmed/35300705
http://dx.doi.org/10.1186/s12987-022-00315-1