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Comprehensive structure and functional adaptations of the yeast nuclear pore complex

Nuclear pore complexes (NPCs) mediate the nucleocytoplasmic transport of macromolecules. Here we provide a structure of the isolated yeast NPC in which the inner ring is resolved by cryo-EM at sub-nanometer resolution to show how flexible connectors tie together different structural and functional l...

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Detalles Bibliográficos
Autores principales: Akey, Christopher W., Singh, Digvijay, Ouch, Christna, Echeverria, Ignacia, Nudelman, Ilona, Varberg, Joseph M., Yu, Zulin, Fang, Fei, Shi, Yi, Wang, Junjie, Salzberg, Daniel, Song, Kangkang, Xu, Chen, Gumbart, James C., Suslov, Sergey, Unruh, Jay, Jaspersen, Sue L., Chait, Brian T., Sali, Andrej, Fernandez-Martinez, Javier, Ludtke, Steven J., Villa, Elizabeth, Rout, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928745/
https://www.ncbi.nlm.nih.gov/pubmed/34982960
http://dx.doi.org/10.1016/j.cell.2021.12.015