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Comprehensive structure and functional adaptations of the yeast nuclear pore complex
Nuclear pore complexes (NPCs) mediate the nucleocytoplasmic transport of macromolecules. Here we provide a structure of the isolated yeast NPC in which the inner ring is resolved by cryo-EM at sub-nanometer resolution to show how flexible connectors tie together different structural and functional l...
Autores principales: | Akey, Christopher W., Singh, Digvijay, Ouch, Christna, Echeverria, Ignacia, Nudelman, Ilona, Varberg, Joseph M., Yu, Zulin, Fang, Fei, Shi, Yi, Wang, Junjie, Salzberg, Daniel, Song, Kangkang, Xu, Chen, Gumbart, James C., Suslov, Sergey, Unruh, Jay, Jaspersen, Sue L., Chait, Brian T., Sali, Andrej, Fernandez-Martinez, Javier, Ludtke, Steven J., Villa, Elizabeth, Rout, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928745/ https://www.ncbi.nlm.nih.gov/pubmed/34982960 http://dx.doi.org/10.1016/j.cell.2021.12.015 |
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