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Pifithrin-α ameliorates glycerol induced rhabdomyolysis and acute kidney injury by reducing p53 activation

OBJECTIVES: Rhabdomyolysis is a series of symptoms caused by the dissolution of striped muscle, and acute kidney injury (AKI) is a potential complication of severe rhabdomyolysis. The underlying causes of AKI are remarkably complex and diverse. Here, we aim to investigate whether pifithrin-α protect...

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Detalles Bibliográficos
Autores principales: Yuqiang, Chen, Lisha, Zhang, Jiejun, Wen, Qin, Xue, Niansong, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928845/
https://www.ncbi.nlm.nih.gov/pubmed/35285384
http://dx.doi.org/10.1080/0886022X.2022.2048857