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Preoperative environment enrichment preserved neuroligin 1 expression possibly via epigenetic regulation to reduce postoperative cognitive dysfunction in mice

AIMS: Postoperative cognitive dysfunction (POCD) is a common and significant syndrome. Our previous studies have shown that surgery reduces dendritic arborization and spine density and that environment enrichment (EE) reduces POCD. Neuroligin 1 is a postsynaptic protein involved in the formation of...

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Detalles Bibliográficos
Autores principales: Min, Jia, Lai, Zhongmeng, Wang, Hui, Zuo, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928916/
https://www.ncbi.nlm.nih.gov/pubmed/34882968
http://dx.doi.org/10.1111/cns.13777