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SerpinA3N attenuates ischemic stroke injury by reducing apoptosis and neuroinflammation

OBJECTIVE: To assess the effect of serine protein inhibitor A3N (serpinA3N) in ischemic stroke and to explore its mechanism of action. METHODS: Mouse ischemic stroke model was induced by transient middle cerebral artery occlusion followed by reperfusion. The expression pattern of serpinA3N was asses...

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Detalles Bibliográficos
Autores principales: Zhang, Yu, Chen, Qianbo, Chen, Dashuang, Zhao, Wenqi, Wang, Haowei, Yang, Mei, Xiang, Zhenghua, Yuan, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928918/
https://www.ncbi.nlm.nih.gov/pubmed/34897996
http://dx.doi.org/10.1111/cns.13776