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The Associations between COMT and MAO-B Genetic Variants with Negative Symptoms in Patients with Schizophrenia
Negative symptoms of schizophrenia, including anhedonia, represent a heavy burden on patients and their relatives. These symptoms are associated with cortical hypodopamynergia and impaired striatal dopamine release in response to reward stimuli. Catechol-O-methyltransferase (COMT) and monoamine oxid...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928957/ https://www.ncbi.nlm.nih.gov/pubmed/34287249 http://dx.doi.org/10.3390/cimb43020045 |