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The Associations between COMT and MAO-B Genetic Variants with Negative Symptoms in Patients with Schizophrenia

Negative symptoms of schizophrenia, including anhedonia, represent a heavy burden on patients and their relatives. These symptoms are associated with cortical hypodopamynergia and impaired striatal dopamine release in response to reward stimuli. Catechol-O-methyltransferase (COMT) and monoamine oxid...

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Detalles Bibliográficos
Autores principales: Madzarac, Zoran, Tudor, Lucija, Sagud, Marina, Nedic Erjavec, Gordana, Mihaljevic Peles, Alma, Pivac, Nela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928957/
https://www.ncbi.nlm.nih.gov/pubmed/34287249
http://dx.doi.org/10.3390/cimb43020045