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Three-Dimensional Reconstructed Bone Marrow Matrix Culture Improves the Viability of Primary Myeloma Cells In-Vitro via a STAT3-Dependent Mechanism

Primary myeloma (PM) cells are short-lived in conventional culture, which limited their usefulness as a study model. Here, we evaluated if three-dimensional (3D) culture can significantly prolong the longevity of PM cells in-vitro. We employed a previously established 3D model for culture of bone ma...

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Detalles Bibliográficos
Autores principales: Huang, Yung-Hsing, Almowaled, Meaad, Li, Jing, Venner, Christopher, Sandhu, Irwindeep, Peters, Anthea, Lavasanifar, Afsaneh, Lai, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928965/
https://www.ncbi.nlm.nih.gov/pubmed/34201211
http://dx.doi.org/10.3390/cimb43010026