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The Androgen Hormone-Induced Increase in Androgen Receptor Protein Expression Is Caused by the Autoinduction of the Androgen Receptor Translational Activity

The androgen receptor (AR) plays a central role in prostate, muscle, bone and adipose tissue. Moreover, dysregulated AR activity is a driving force in prostate cancer (PCa) initiation and progression. Consequently, antagonizing AR signalling cascades via antiandrogenic therapy is a crucial treatment...

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Detalles Bibliográficos
Autores principales: Siciliano, Tiziana, Sommer, Ulrich, Beier, Alicia-Marie K., Stope, Matthias B., Borkowetz, Angelika, Thomas, Christian, Erb, Holger H. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928990/
https://www.ncbi.nlm.nih.gov/pubmed/35723327
http://dx.doi.org/10.3390/cimb44020041